Spinal Chordomas: Current Medical and Surgical Management
نویسندگان
چکیده
Chordomas are rare, benign tumors that account for 1-4% of bony lesions and most frequently occur in the skull base, mobile spine, and sacrum. Historically, they have been most effectively managed with en bloc surgical resection, as they are resistant to conventional radiotherapy and chemotherapy. Currently, the gold standard treatment for spinal chordomas is en bloc excision with negative margins followed by postoperative external-beam radiation therapy. However, with recent technological advances in radiation delivery and the discovery of potential targeting sites, the role of both radiation therapy and chemotherapy is gaining prominence [1].
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